- Reducing the risk of blood clots
- Reducing low-density lipoprotein (LDL, or "bad") cholesterol
- Preventing damage to blood vessels in your heart
- Helping maintain a healthy blood pressure
Both red wine and grape juice also contain antioxidants called flavonoids, which have been shown to increase your high-density lipoprotein (HDL, or "good") cholesterol and lower your risk of clogged arteries (atherosclerosis), and may help lower blood pressure.
Benefit of Grapes: Lower Blood Pressure, Reduced Heart Damage
A University of Michigan Cardiovascular Center study suggests grapes may prevent heart health risks beyond the simple blood pressure-lowering impact that can come from a diet rich in fruits and vegetables. The benefits may be the result of the phytochemicals – naturally occurring antioxidants – turning on a protective process in the genes that reduces damage to the heart muscle.
The study, performed in laboratory rats, was presented at the 2009 Experimental Biology convention in New Orleans. Although the current study was supported in part by the California Table Grape Commission, which also supplied the grape powder, the authors note that the commission played no role in the study's design, conduct, analysis or the preparation of the journal article for publication. E. Mitchell Seymour, M.S., also received funding from the National Heart, Lung and Blood Institute, part of the National Institutes of Health, through a National Research Service Award.
Heart cells, like other cells in the body, make an antioxidant protein called glutathione, which is one of our first defenders against damaging oxidative stress. High blood pressure causes oxidative stress in the heart and lowers the amount of protective glutathione. However, intake of grapes actually turned on glutathione-regulating genes in the heart and significantly elevated glutathione levels.
Each group of 12 rats was fed the same weight of food each day with powdered grapes making up 3 percent of the diet (by weight) for rats that received grapes as part of either a low-salt or high-salt diet. The rats that received hydrazine were fed it through their water supply in a dose that has been previously shown to be effective in reducing blood pressure.
"There are the small changes that diet can bring, but the effect of grape intake on genes can have a greater impact on disease down the road," said E. Mitchell Seymour, M.S., who led the research as part of his doctoral work in nutrition science at Michigan State University to reduce other potentially harmful molecular and cellular activity in the body.